Biomaterials and Tissue Engineering

The Shanghai Institute of Ceramics, Chinese Academy of Sciences has been researching biomedical materials since the 1980s and established the Center of Biomaterials and Tissue Engineering in 2001. Since its establishment, the center has focused on basic and applied research on nanobiomaterials, tissue engineering scaffold materials, biomaterial surfaces and interfaces, and organoid materials and devices. After more than 20 years of unremitting efforts, the Biomaterials and Tissue Engineering Research Center has five research groups and 33 permanent employees, including eight research fellows, ten associate researchers, and 15 scientific research and engineering technicians.

The Center actively strengthens cooperation with domestic and foreign units. Overseas cooperation units include the Queensland University of Technology in Australia, the University of New South Wales, the University of Sydney, the City University of Hong Kong, the University of Western Ontario in Canada, the French National Center for Scientific Research, and Nanyang Technological University in Singapore, etc. Domestic cooperative units include Shanghai Jiao Tong University, Zhejiang University, Wuhan University, Fudan University, the Ninth People's Hospital of Shanghai Jiao Tong University, Shanghai Sixth People's Hospital, Suzhou Medical College, Huashan Hospital, Xinhua Hospital and Changzheng Hospital, etc. universities and hospitals.

Director:Xuanyong Liu

Deputy Director:Yufang Zhu

Research Fields:

1. Bioactive materials and tissue engineering scaffolds

(1) The degradable bioactive materials for tissue repair and tissue engineering applications (including bioactive glasses, bioactive ceramics, biopolymers, bioactive composites, nanobiomaterials, and scaffolds)

(2) The biomaterials for drug delivery and the research on drug release system (the organic/inorganic composites with nano-structure for delivery)

(3) The mechanism of cell-biomaterials interaction (effects of the material on the adhesion, proliferation, differentiation, and gene expression of cells)

(4) Characterization of the physical and chemical properties and biocompatibility evaluation of biomaterials.

2. Nano-biomaterials for controlled drug release, bio-labelling and diagnostic

(1) Preparation and properties of nano-biomaterials and nanocomposites

(2) Semiconductor quantum dots: preparation, self-assembly and their applications

(3) Microwave-assisted rapid synthesis of low-dimensional nanomaterials and nanocomposites

3. The research and development of inorganic bioactive coating techniques for medical implants

(1) Nanosized and Functionalized Surface of Ti alloys for Biomedical application

(2) Surface Modification of Biomaterials Using Plasma Immersion Ion Implantation and Deposition Technology

(3) Plasma Sprayed Bioactive Ceramic Coatings

4. Development of biomaterials and devices for organoid culture in biomedical engineering

(1) Development of organoid culture for hard and soft tissue/organs

(2) Biomaterials for organoid culture for tissue engineering and 3D bioprinting

(3) Microfluidic and organoid-on-a-chip devices for high throughput organoids culture

List of Research Groups: 

(1) Biomaterials and Tissue Engineering Research Group

Group Leader:Chengtie Wu

Deputy Group Leader: Yufang Zhu, Zhiguang Huan  

(2) Biomaterials Surface & Interfaces Group

Group Leader:Xuanyong Liu

(3) Bio-nano-technology Research Group

Group Leader:Yingjie Zhu

(4) PI Hongxu Lv

(5) PI Pu Xiao